Isku duro Enrofloxacin

Pharmacodynamic Enrofloxacin waa daawo bakteeriya-bakteeriya ah oo ballaaran oo si gaar ah loogu isticmaalo xayawaanka fluoroquinolone.Waayo e.coli, salmonella, klebsiella, brucella, pasteurella, pleuropneumonia actinobacillus, erysipelas, bacillus proteus, clayey bakteeriyada Mr Charest, corynebacterium suppurative, bakteeriyada dhariga dhiiga ee jabtay, staphylococcus aureus, mycoplasma, chlamygin, iyo wixii la mid ah oo dhan waxay leeyihiin saameyn wanaagsan oo ah peruudose. iyo streptococcus waa daciif, saameyn daciif ah bakteeriyada anaerobic.Waxay leedahay saameyn cad ka dib-bakteeriyadu waxay ku leedahay bakteeriyada xasaasiga ah.Habka ficilka bakteeriyada ee alaabtani waa in la joojiyo wareegga DNA-da bakteeriyada, farageliya soo-celinta, qorista iyo hagaajinta dib-u-habaynta DNA-da bakteeriyada, bakteeriyadu si caadi ah uma kori karto oo uma taran karto oo dhimanayso.

Pharmacokinetics Daawadu si dhakhso ah oo buuxda ayaa loo nuugay cirbadeynta muruqa.bioavailability-ku wuxuu ahaa 91.9% doofaarka iyo 82% lo'da.Waxay si weyn ugu qaybsan tahay xayawaanka waxayna si fiican u geli kartaa unugyada iyo dareeraha jidhka.Marka laga reebo dareeraha cerebrospinal, fiirsashada daawada ee ku dhawaad ​​dhammaan unugyada ayaa ka sarreeya tan plasma.Dheef-shiid kiimikaad ee ugu weyn waa ka saarida ethyl ee giraanta 7-piperazine si loo soo saaro ciprofloxacin, oo ay ku xigto oksaydheynta iyo glucuronic acid.Inta badan kelyaha (dheecaanka tubbada kelyaha iyo shaandhaynta glomerular), dheecaanka 15% ~ 50% oo ah qaabka asalka ah ee kaadida.Ciribtirka nolosha nuska ah ee cirbadeynta muruqyada gudaha waxay ahayd 5.9 saacadood lo'da caanaha, 1.5 ~ 4.5 saacadood oo idaha ah, iyo 4.6 saacadood oo doofaarro ah.